Hydrogen fluoride

Bioaccumulation: aquatic / sediment

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

bioaccumulation in aquatic species, other

Remarks:

Published bioaccumulation data

Type of information:

other: review

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

Various studies summarised in EU RAR and Dutch ICD

Qualifier:

no guideline followed

Principles of method if other than guideline:

The EU RAR summarises the results of a number of studies

GLP compliance:

not specified

Specific details on test material used for the study:

Although sodium fluoride has been identified as the test material for the current study summary, it should be noted that the publication (EU RAR for hydrogen fluoride (2001)) reports bioaccumulation data for various fluoride species, not just sodium fluoride.

Radiolabelling:

no

Test organisms (species):

not specified

Route of exposure:

aqueous

Type:

BCF

Value:

53 - 58 L/kg

Basis:

whole body d.w.

Remarks on result:

other: Freshwater Fish

Remarks:

(Sloof et al., 1988)

Type:

BCF

Value:

< 2 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Freshwater Fish

Remarks:

(Sloof et al., 1988)

Type:

BCF

Value:

3.2 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Freshwater mollusca- Chaisemartin

Type:

BCF

Value:

7.5 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Freshwater Aquatic macrophyta - Chaisemartin

Type:

BCF

Value:

149 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Seawater fish

Remarks:

(Hemens and Warwick, 1972)

Type:

BCF

Value:

27 - 62 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Seawater Crustacea

Remarks:

(Hemens and Warwick, 1972)

Type:

BCF

Value:

30 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Seawater Fish

Remarks:

(Sloof et al., 1988)

The limited data indicate that fluoride biomagnification in the aquatic environment is of little significance. Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissues.

Conclusions:

In freshwater aquatic organisms it was found that the fluoride accumulates primarily in the exoskeleton of crustacea and in the bones of fish. In an experimental marine ecosystem with fish, crustaceans and plants, F was found to accumulate in all species.

Executive summary:

In freshwater aquatic organisms it was found that the fluoride accumulates primarily in the exoskeleton of crustacea and in the bones of fish. In fish, the BCF value was between 53 -58 (d.w.) and <2 (w.w.). In crustacea, BCF value was <1 (d.w.). The highest reported BCF value for mollusca and aquatic macrophyta were 3.2 and 7.5 (w.w) respectively.

In an experimental marine ecosystem with fish, crustaceans and plants, F was found to accumulate in all species. The highest value, 149, was found in marine fish. BCF values for crustacea range from 27 to 62 (Hemens and Warwick, 1972). Fluoride concentrations up to 30 mg F/kg were found in consumption fish (Slooff et al, 1988). The limited data indicate that fluoride biomagnification in the aquatic environment is of little significance. Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissue

Reference 2

Endpoint:

bioaccumulation in aquatic species, other

Remarks:

Published bioaccumulation data

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Justification for type of information:

Hydrogen fluoride is known to rapidly react upon contact with water to form fluoride, therefore available data from studies with fluoride are given as indication of bioaccumulation properties of hydrogen fluoride.

Reason / purpose for cross-reference:

read-across source

Type:

BCF

Value:

53 - 58 L/kg

Basis:

whole body d.w.

Remarks on result:

other: Freshwater Fish

Remarks:

(Sloof et al., 1988)

Type:

BCF

Value:

< 2 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Freshwater Fish

Remarks:

(Sloof et al., 1988)

Type:

BCF

Value:

3.2 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Freshwater mollusca- Chaisemartin

Type:

BCF

Value:

7.5 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Freshwater Aquatic macrophyta - Chaisemartin

Type:

BCF

Value:

149 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Seawater fish

Remarks:

(Hemens and Warwick, 1972)

Type:

BCF

Value:

27 - 62 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Seawater Crustacea

Remarks:

(Hemens and Warwick, 1972)

Type:

BCF

Value:

30 L/kg

Basis:

whole body w.w.

Remarks on result:

other: Seawater Fish

Remarks:

(Sloof et al., 1988)

The limited data indicate that fluoride biomagnification in the aquatic environment is of little significance. Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissues.

Conclusions:

In freshwater aquatic organisms it was found that the fluoride accumulates primarily in the exoskeleton of crustacea and in the bones of fish. In an experimental marine ecosystem with fish, crustaceans and plants, F was found to accumulate in all species.

Executive summary:

Hydrogen fluoride is known to rapidly react upon contact with water to form fluoride, therefore available data from studies with fluoride are given as indication of bioaccumulation properties of hydrogen fluoride.

In freshwater aquatic organisms it was found that the fluoride accumulates primarily in the exoskeleton of crustacea and in the bones of fish. In fish, the BCF value was between 53 -58 (d.w.) and <2 (w.w.). In crustacea, BCF value was <1 (d.w.). The highest reported BCF value for mollusca and aquatic macrophyta were 3.2 and 7.5 (w.w) respectively.

In an experimental marine ecosystem with fish, crustaceans and plants, F was found to accumulate in all species. The highest value, 149, was found in marine fish. BCF values for crustacea range from 27 to 62 (Hemens and Warwick, 1972). Fluoride concentrations up to 30 mg F/kg were found in consumption fish (Slooff et al, 1988). The limited data indicate that fluoride biomagnification in the aquatic environment is of little significance. Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissue

Description of key information

Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissue

Key value for chemical safety assessment

BCF (aquatic species):

149 L/kg ww

Additional information

In freshwater aquatic organisms it was found that the fluoride accumulates primarily in the exoskeleton of crustacea and in the bones of fish. In fish, the BCF value was between 53 -58 (d.w.) and <2 (w.w.). In crustacea, BCF value was <1 (d.w.). The highest reported BCF value for mollusca and aquatic macrophyta were 3.2 and 7.5 (w.w) respectively.

In an experimental marine ecosystem with fish, crustaceans and plants, F was found to accumulate in all species. The highest value, 149, was found in marine fish. BCF values for crustacea range from 27 to 62. Fluoride concentrations up to 30 mg F/kg were found in consumption fish. The limited data indicate that fluoride biomagnification in the aquatic environment is of little significance. Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissue