Registration Dossier
Registration Dossier
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EC number: 203-275-7 | CAS number: 105-16-8
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- other: case report
- Adequacy of study:
- supporting study
- Study period:
- 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: published data, single data
Data source
Reference
- Reference Type:
- publication
- Title:
- A Case of Occupational, Allergic Contact Dermatitis from Diethyl-amino-ethyl Methacrylate (DEMA)
- Author:
- Higashi, J.
- Year:
- 2 003
- Bibliographic source:
- Skin Research, 2: 414-417, 2003
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- case report
Test guideline
- Qualifier:
- no guideline required
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-(diethylamino)ethyl methacrylate
- EC Number:
- 203-275-7
- EC Name:
- 2-(diethylamino)ethyl methacrylate
- Cas Number:
- 105-16-8
- Molecular formula:
- C10H19NO2
- IUPAC Name:
- 2-(diethylamino)ethyl methacrylate
- Test material form:
- other: liquid
Constituent 1
Method
- Type of population:
- occupational
- Ethical approval:
- not applicable
- Subjects:
- A 36-year-old Japanese that handled DEMA in his working place.
- Clinical history:
- - Symptoms, onset and progress of the disease and exposure history:
The person concerned/ affected was exposed to DEMA from Jan. 7, 2002. He noticed pruritus on his hands at midnight of Jan. 19. Edematous erythema developed on his both hands on the morning of Jan. 20. He consulted his neighboring physician and took sick leave until Jan. 24. He returned to work on Jan. 25 using new vinyl gloves. He handled DEMA again on Feb. 21. On the next morning, edematous erythema appeared again on his both hands. He consulted to Kashiwara municipal hospital where he passed a precise medical examination. - Controls:
- Not applicable
Results and discussion
- Results of examinations:
- RESULT OF CASE REPORT:
It was proved by patchtest that the allergic reactions that a 36 year old Japanese man experienced while handling DEMA at his working place are caused indeed by DEMA.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
