Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

No mineral fibres including this substance have shown acute toxic effects

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

No mineral fibre, including this substance, has shown acute toxic effects, even after very large inhalation exposures and instillation studies where physical damage was avoided. No treatment related lethality or acute damage to any organ system has been detected in chronic or sub-chronic studies with the fibre under discussion in this dossier. Calcium and magnesium silicates are listed as E numbers (E552 and E553a) in Europe indicating no acute toxic effects are associated with similar chemical compositions.


Justification for classification or non-classification

No acute effects have been detected with this substance or other fibrous materials, dosing at a sufficient rate to cause acute effects is not possible as the substance will physically interfer with many physiological functions including breathing and ingestion.