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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07 October 2008 to 27 February 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study performed according to GLP and internationally accepted test guidelines.
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Key result
Water solubility:
> 1 000 g/L
Conc. based on:
test mat.
Remarks on result:
other: An accurate quantitative result was not obtained because the preliminary test indicated that the water solubility is in excess of 1000 mg/mL. Temperature and pH of the solution were not specified.
Details on results:
In a preliminary test, a portion (approximately 500 mg) of the test substance was found to dissolve readily in 0.5 ml of purified water, indicating a solubility of greater than 1000 g/l of water. No further testing was considered necessary. Temperature and pH were not specified

Temperature and pH were not specified as a preliminary test (see results above) indicated further testing was not necessary.

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be greater than 1000 g/l of water.
Executive summary:

A package of physico-chemical testing including a water solubility test was conducted to determine specific properties of the test substance 1,3-Bis(aminomethyl)cyclohexane. The water solubility test was performed to OECD and EC test guidelines, and in compliance with GLP.

In a preliminary test, a portion (approximately 500 mg) of the test substance was found to dissolve readily in 0.5 ml of purified water, indicating a solubility of greater than 1000 g/l of solvent. No further testing was considered necessary.

The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be greater than 1000 g/l of water.

Description of key information

The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be >1000 g/L of water. However, the key value for water solubility was determined at 100 g/L at 25 °C as this is the advised maximum value in EUSES.

Key value for chemical safety assessment

Water solubility:
100 g/L
at the temperature of:
25 °C

Additional information

A package of physico-chemical testing including a water solubility test was conducted to determine specific properties of the test substance 1,3-Bis(aminomethyl)cyclohexane. The water solubility test was performed to OECD and EC test guidelines, and in compliance with GLP. In a preliminary test, a portion (approximately 500 mg) of the test substance was found to dissolve readily in 0.5 ml of purified water, indicating a solubility of greater than 1000 g/l of water. No further testing was considered necessary. The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be greater than 1000 g/l of water.

However, the key value for water solubility was determined at 100 g/L at 25 °C as this is the advised maximum value in EUSES.