Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Sodium chloride is considered to be slightly to not irritating to the skin, and moderately irritating to the eyes

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Sodium chloride is categorised under GRAS (Generally Recognised as Safe) by the FDA (U.S. Food and Drug Administration). Based on the studies available for skin and eye irritation/corrosion, sodium chloride is considered to be slightly to not irritating to the skin, and slightly irritating to the eyes.

There are no data available on the respiratory irritation potential for sodium chloride, but based on results of skin and eye irritation tested, would not be expected to be irritating.


Effects on eye irritation: moderately irritating

Effect level: empty Endpoint conclusion: Adverse effect observed

Justification for classification or non-classification

Sodium chloride is not formally classified in the EU (according to Regulation EC No. 1272/2008 Annex VI, Table 3.1 and Regulation EC No. 1272/2008 Annex VI, Table 3.2).

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