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Ecotoxicological information

Toxicity to birds

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Description of key information

Sodium Bromide: An Acute Oral Toxicity Study with the Bobwhite
21-Day Acute Oral LD50 Study with Sodium Bromide Technical in Mallard Ducks
Sodium Bromide: A Dietary LC50 Study with the Bobwhite
Sodium Bromide: A Dietary LC50 Study with the Mallard

Key value for chemical safety assessment

Short-term EC50 or LC50 for birds:
5 633 mg/kg food

Additional information

An acute toxicity test was conducted according to FIFRA guideline 71-1 and ASTM Standard E857-81. Bobwhite quail (Colinus virginianus) and mallard duck (Anas platyrhynchos) were given single oral doses of sodium bromide by gavage and monitored for 14 days afterwards – 10 birds per dose group were tested. No mortalities occurred in any dose groups of bobwhite quail. When compared to controls, there was no effect on body weight or feed consumption at any dosage level. Various signs of toxicity were observed in each dose groups at some point during the first week except the lowest dose and control groups. No signs persisted into the second week of observation. No mortalities occurred during the course of the study for mallard duck. Signs of toxicity typical of intoxication with sodium bromide included slight to severe ataxia (increasing with external stimuli), wing droop, lethargy, ventral head curl, and loss of righting reflex. When compared with the controls there was no effect on body weight or consumption at any of the concentrations tested. The 5-d LC50 > 5633 mg/kg for both species.