Registration Dossier

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Reference
Reference Type:
publication
Title:
Three cases of allergic contact dermatitis to 4,4'-diaminodiphenylmethane
Author:
Grimalt, Vilaplana and Romageura
Year:
2009
Bibliographic source:
Contact Dermatitis, 60: 346-347

Materials and methods

Type of sensitisation studied:
skin
Study type:
case report
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Type of population:
not specified
Details on study design:
Three cases were patch tested with 2 day occlusion against the European baseline series and a shoe and diisocyanate series.

Results and discussion

Results of examinations:
All patch tests were negative except for 4,4'-MDA, 0.5% pet. (++ on D2 and D4).

Applicant's summary and conclusion