Registration Dossier
Registration Dossier
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EC number: 275-735-5 | CAS number: 71630-92-7 Substance obtained by burning the husk removed from the rice paddy. Contains silica as well as the elements aluminum, calcium, carbon, chromium, copper, indium, iron, lead, magnesium, manganese, molybdenum, phosphorus, silver, sodium, tin, and zinc.
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
No information is available on toxic effects of rice husk ashes or crystalline silica to reproduction in laboratory animals. Furthermore, no reproductive effects in humans have been reported (IPCS, 2000). The toxicity to reproduction of amorphous silica (Aerosil R 972) has been investigated in a one-generation study in rats orally exposed to 500 mg/kg bw by feed over 6 months. No reproductive effects were observed at this dose level (Lewinson, 1994).
Short description of key information:
There are no available data on the reproductive effects of rice husk ashes or crystalline silica in laboratory animals. There are no reports suggesting or indicating such effects in humans.
Effects on developmental toxicity
Description of key information
There are no available data on the developmental/teratogenic effects of rice husk ashes or crystalline silica in laboratory animals. There are no reports suggesting or indicating such effects in humans.
Additional information
No information is available on developmental/teratogenic effects of rice husk ashes or crystalline silica in laboratory animals. Furthermore, no effects in humans have been reported (IPCS, 2000). The developmental toxicity of amorphous silica (Aerosil R 972) has been investigated in a one-generation study in rats orally exposed to 500 mg/kg bw by feed over 6 months. No developmental/teratogenic effects were observed in the litters of the dams exposed at this dose level (Lewinson, 1994). In other studies, a higher oral NOEL value (1600 mg/kg bw/day) for maternal and developmental toxicity has been reported for rat, mouse, hamster and rabbit mice (OECD SIDS, 2004).
Justification for classification or non-classification
No conclusive data available
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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