Registration Dossier
Registration Dossier
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EC number: 232-304-6 | CAS number: 8002-26-4 A complex combination of tall oil rosin and fatty acids derived from acidulation of crude tall oil soap and including that which is further refined. Contains at least 10% rosin.
Endpoint summary
Administrative data
Description of key information
Reliable results are available from short-term tests with fish, aquatic invertebrates and algae. LL50/EL50 values determined in tests conducted with water-accommodated fractions (WAFs) of DTO were >100, between 5000 and 10000 and circa 3300 mg/L for Danio rerio (fish), Daphnia magna (invertebrate) and Scenedesmus subspicatus (algae) respectively. A NOELR of circa 300 mg/L was also determined in the test with S. subspicatus. These values are representative of results obtained in reliable tests carried out on different samples of DTO.
No measured data are available for long-term toxicity of DTO to fish. A data-waiver is considered to be appropriate for this endpoint on the following grounds:
- The results from short-term tests indicate that fish, invertebrates and algae are similarly susceptible to the substance. Reliable long-term test data for Crude Tall Oil (CAS No. 8002 -26 -4) show an absence of toxicity to invertebrates at a loading rate of 1 mg/L. The NOELR for algae is also >1 mg/L.
Testing for long-term toxicity to fish will not therefore contribute to the database that is required to complete the assessment of the substance.
A reliable 21-day NOELR of ≥1 mg/L has been determined for the effects of the closely-related substance, Crude Tall Oil (CAS No. 8002 -26 -4) on reproduction, growth and mortality of Daphnia magna. The result has been used for read-across to DTO. The result was obtained in a test conducted on a sample of CTO that showed the highest toxicity in a number of short-term tests with D. magna.
Additional information
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