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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute toxicity studies are available for fish daphnia and algae. For fish the 96h LC50 is >100 mg/L. For daphnia the 48h LC50 for piperazine is observed to be 105.4 mg/L (95% CI: 86.6 - 127.2 mg/L). For Algae 72h ErC50 and ErC10 for piperazine is observed to be 153.1 and 109.3 mg/L respectively.

From the available data Daphnia appear to be the most sensitive aquatic species. The value for long-term toxicity to Daphnia which resulted in a NOEC of 12.5 mg/L is used for calculation of PNEC.

The long-term toxicity to fish is derived using the Acute-to-Chronic (ACR) approach. Based on the available 96-h LC50 > 100 mg/L (NITE, 2003) a NOEC for the long-term toxicity to fish of > 1 mg/L was derived.