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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Endpoint summary

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Administrative data

Description of key information

An LLNA study was conducted in 2010 (Sanders 2010). This study showed that TPP is a strong skin sensitiser.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

TPP showed positive reactions at test concentrations of 2.5%, 5%, and 10% in a new local lymph node assay (LLNA) (Harlan 2010). The EC3 value from the study was determined to be 1.4%.

Migrated from Short description of key information:
EC3 = 1.4%; TPP is a skin sensitiser.

Justification for classification or non-classification

TPP has been classified as Skin Sens. 1.