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Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-09-15 to 2008-09-22
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
- Stability of the test substance is missing. - i) no method validation was performed (ii) no determination at 10 and 30 °C was performed, hence no conclusion possible if the water solubility of the substance is dependent on temperature (iii) no GLP certificate available Remark: Due to the fact that a further water solubility study (k_Walker_and_White_2008_water_solubility) was performed in a second laboratory with this test substance with analogue results the study could be regarded as valid.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
adopted 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
, 1992
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
348 040 mg/L
Temp.:
20 °C
pH:
ca. 6.29
Details on results:
During this study the water solubility at 20 °C was determined and found to be 348.04 g/L based on a measured concentration of 82.35 g Co/L (+/- 2.325 g Co/L) using the flask shaking method.
Conclusions:
Interpretation of results: very soluble (> 10000 mg/L)
During this study the water solubility at 20 °C was determined and found to be 348040 mg/L based on a measured concentration of 82.35 g Co/L (+/- 2.325 g Co/L) using the flask shaking method.
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-09-13 to 2008-10-01
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
360 g/L
Temp.:
20 °C
pH:
5.6
Details on results:
Mean test material concentration: 360 g/L at 20.0 +/- 0.5°C
Range: 352 to 367g/L
Conclusions:
Interpretation of results: very soluble (> 10000 mg/L)
The water solubility of the test material has been determined to be 360 g/L of solution, at 20.0 +/- 0.5°C.

Description of key information

Cobalt diacetate has a water solubility of 348040 mg/L and of 360 g/L at 20 °C. The median of 354 g/L will be used for CSA.

Key value for chemical safety assessment

Water solubility:
354 g/L
at the temperature of:
20 °C

Additional information