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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

No long-term fish toxicity tests are available for the test substance. It appears appropriate to waive this study.

Key value for chemical safety assessment

Additional information

The test substance is covered by the category approach of methylenediphenyl diisocyanates (MDI). Hence, data of the category substances can be used to cover this endpoint.

The test substances of the methylenediphenyl isocyanate (MDI) category react quickly with water and hence will be rapidly hydrolysed in contact with aqueous media (T1/2 = 20h). However, MDI is hydrophobic and poorly soluble in water and thus the heterogeneous reaction with water or soil is less rapid. The major product of such a reaction is a solid, insoluble polyurea. Under conditions typical of many types of environmental contact, i. e. with relatively poor dispersion of the denser isocyanate, the interfacial reaction leads to the formation of a solid crust encasing partially or unreacted material. This crust restricts ingress of water and egress of amine, and hence slows and modifies hydrolysis.