Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: Toxicokinetics assessment
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Based on the known physico-chemical properties and the available toxicologic studies, a justified assessment of the toxicokinetic and biotransformational properties of HDI Trimer MEKO-blocked could be made, therefore an in vivo toxicokinetic study is at present not an urgent requirement.

Data source

Reference
Reference Type:
other: Toxicocinetics assessment
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Principles of method if other than guideline:
Assessment of Toxicokinetics

Test material

Constituent 1
Reference substance name:
85940-94-9
Cas Number:
85940-94-9
IUPAC Name:
85940-94-9

Results and discussion

Any other information on results incl. tables

Based on the known physico-chemical properties and the available toxicologic studies, a justified assessment of the toxicokinetic and biotransformational properties of HDI Trimer MEKO-blocked could be made, therefore an in vivo toxicokinetic study is at present not an urgent requirement.

Applicant's summary and conclusion