Pentane-2,4-dione

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1992

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: guideline study with limited documentation

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

1992

Report date:

1992

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))

Deviations:

no

Principles of method if other than guideline:

The test was conducted in accordance with "Biodegradation test of chemical substance by microorganisms etc." stipulated in the Order
Prescribing the Items of the Test Relating to the New Chemical Substance (1974, Order of the Prime Minister, the Minister of Health and Welfare, the
Minister of International Trade and Industry No. 1). This guideline corresponds to "301C, Ready Biodegradability: Modified MITI Test (I)" stipulated in the OECD Guidelines for Testing of Chemicals (1981).

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Pentane-2,4-dione

EC Number:

204-634-0

EC Name:

Pentane-2,4-dione

Cas Number:

123-54-6

Molecular formula:

C5H8O2

IUPAC Name:

pentane-2,4-dione

Details on test material:

no data

Specific details on test material used for the study:

Details on properties of test surrogate or analogue material (migrated information):
no data

Study design

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge (adaptation not specified)

Details on inoculum:

Sludge concentration: 30 mg/l

Duration of test (contact time):

28

Initial test substance concentration

Initial conc.:

100 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation

Parameter followed for biodegradation estimation:

CO2 evolution

Details on study design:

not reported

Reference substance

Reference substance:

not specified

Results and discussion

Preliminary study:

not reported

Test performance:

not reported, according to guideline

% Degradation

Parameter:

% degradation (CO2 evolution)

Value:

83 - 100

Sampling time:

28 d

Details on results:

Indirect Analysis: BOD 83%
Direct Analysis: GC 100% ; TOC 95%

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

Substance is readily biodegradable under the conditions used.

Executive summary:

A readily biodegradability test was performed with 2,4 -Pentanedione according to OECD 301C, Ready Biodegradability: Modified MITI Test (I). The concentration of the substance was 100 mg/l whereas the activated sludge concentration was 30 mg/l. The test showed a readily biodegradation of more than 80% after 28 days of exposure.