Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

KEY_404_1989_Hoechst_89.0389: not irritating, not corrosive
NON KEY_404_1974_LONZA_Dec 23, 1974: not irritating, not corrosive
NON KEY_404_1978_BASF_11.07.78 (dd): not irritating, not corrosive
KEY_405_1989_Hoechst_89.0409: not irritating
NON KEY_405_1978_BASF_11.07.78 (dd): not irritating

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Skin irritation

In a reliable key study one of three rabbits showed only a very slight and fully reversible erythema response (mean score 0.3). No other signs of irritation or corrosion were observed. So mean scores for all irritation parameters were below threshold values. Findings of two non-key studies are not inconsistent with these data.

Eye irritation

In a reliable key study two of three rabbits showed only a very slight and fully reversible conjunctivae responses (mean score 0.3 and 0.7). No other signs of irritation or corrosion were observed. So mean scores for all irritation parameters were below threshold values. Findings of a non-key studies are not inconsistent with these data.

Justification for classification or non-classification

Skin irritation

Mean scores for all irritation parameters were below threshold values. Based on that the test substance ist neither skin irritant nor skin corrosive.

Eye irritation

Mean scores for all irritation parameters were below threshold values. Based on that the test substance ist not eye irritating.