Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-752-2 | CAS number: 9014-01-1
Manufacture, use & exposure
Manufacture
Documentsopen allclose all
Manufacture
- Name:
- Subtilisin
- Type of composition:
- legal entity composition of the substance
- State / form:
- solid: particulate/powder
- Reference substance:
- Subtilisin
- Reference substance:
- Subtilisin
- Reference substance:
- Subtilisin
- Reference substance:
- Subtilisin
- Reference substance:
- Subtilisin
- Name of activity / technique:
- Manufacture of enzyme concentrate (Manufacturing)
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
- Name of activity / technique:
- Manufacture of enzyme concentrate (Manufacturing)
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- PROC 4: Chemical production where opportunity for exposure arises
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Reference
Contributing activity / technique for the environment
Contributing activity / technique for workers
Manufacture
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Manufacture of substances
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Batch process; Closed systems
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Batch process; Use in semi-closed process with opportunity for exposure
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Transfer of substance or mixture (charging/discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Process sampling
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Equipment cleaning and maintenance
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Name of activity / technique:
- Laboratory activities
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- site specific biological STP
- Application of site specific biological STP sludge on agricultural soil:
- no
Conditions and measures related to external treatment of waste (including article waste)
- Particular considerations on the waste treatment operations:
- no
Other conditions affecting environmental exposure
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- wastewater
- Release estimation method:
- estimated release factor
- Remarks:
- Hanko 2014
- Release from the site to::
- ambient air
- Release estimation method:
- estimated release factor
- Remarks:
- 0
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
- Remarks:
- 0
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Fermentation
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Cell separation/Drum filtration
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Mash treatment/Filtration
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Sampling
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Maintenance, manual cleaning and waste handling
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Laboratory activities
Manufacture
Contributing activity / technique for the environment
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workers
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- PROC 15: Use as laboratory reagent
Manufacture
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Manufacture of the substance
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Batch process; Closed systems
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Batch process; Use in semi-closed process with opportunity for exposure
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Transfer of substance or mixture (charging/discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Equipment cleaning and maintenance
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Name of activity / technique:
- Laboratory activities
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- air
Effectiveness
- Route affected:
- air
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- site specific biological STP
- Application of site specific biological STP sludge on agricultural soil:
- no
Conditions and measures related to external treatment of waste (including article waste)
- Particular considerations on the waste treatment operations:
- no
Other conditions affecting environmental exposure
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- wastewater
- Release estimation method:
- estimated release factor
- Remarks:
- 2014
- Release from the site to::
- ambient air
- Release estimation method:
- measured release rate
- Remarks:
- 2020
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
- Remarks:
- 0
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Geographical location of manufacturing site
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Geographical location of manufacturing site
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Fermentation
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Cell separation/Filtration
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Mash treatment and Ultrafiltration/Microfiltration
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Maintenance, manual cleaning and waste handling
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Laboratory activities
Manufacture
Contributing activity / technique for the environment
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Handle substance within a closed system.
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- With sample collection; Handle substance within a closed system.
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
Transfer of substance or mixture (charging/discharging) at dedicated facilities- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
Use of the substance within laboratory settings, including material transfers and equipment cleaning- Process category (PROC):
- PROC 15: Use as laboratory reagent
Manufacture
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Manufacture of enzyme concentrate
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Manufacture of enzyme concentrate - assumption total liquid handling; prevention of aerosols
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacture of enzyme concentrate - assumption total liquid handling; prevention of aerosols
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacture of enzyme concentrate - assumption total liquid handling; prevention of aerosols
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacture of enzyme concentrate - assumption total liquid handling; prevention of aerosols
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- site specific biological STP
- Application of site specific biological STP sludge on agricultural soil:
- no
Other conditions affecting environmental exposure
Other conditions of use
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- wastewater
- Release estimation method:
- SpERC
- Remarks:
- BASF manufacturing of Subtilisin - Lu
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- SpERC
- Remarks:
- BASF manufacturing of Subtilisin - Lu
- Release from the site to::
- ambient air
- Release estimation method:
- SpERC
- Remarks:
- BASF manufacturing of Subtilisin - Lu
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Other conditions affecting workers exposure
OtherCondRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Other conditions affecting workers exposure
OtherCondRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Other conditions affecting workers exposure
OtherCondRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Other conditions affecting workers exposure
OtherCondRepopen allclose all
Manufacture
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workers
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- PROC 4: Chemical production where opportunity for exposure arises
Manufacture
Contributing activity / technique for the environment
- Name of activity / technique:
- Manufacture of substilisin
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Use in closed batch process
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in batch process where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Transfer of substance/mixture from/to containers at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Transfer of substance/mixture from/to containers at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Use as laboratory reagent
- Process category (PROC):
- PROC 15: Use as laboratory reagent
Manufacture
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Manufacture of substances
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Batch process; Closed systems
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Batch process; Use in semi-closed process with opportunity for exposure
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Transfer of substance or mixture (charging/discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Equipment cleaning and maintenance
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Name of activity / technique:
- Laboratory activities
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- site specific biological STP
- Application of site specific biological STP sludge on agricultural soil:
- no
Conditions and measures related to external treatment of waste (including article waste)
- Particular considerations on the waste treatment operations:
- no
Other conditions affecting environmental exposure
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- wastewater
- Release estimation method:
- estimated release factor
- Remarks:
- Data from other site
- Release from the site to::
- ambient air
- Release estimation method:
- estimated release factor
- Remarks:
- 0
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
- Remarks:
- 0
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Fermentation and Cell separation/Micro-filtration
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Cell separation/Filtration - outside the room
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Cell separation/Filtration - inside the room
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Mash treatment - outside the room
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Mash treatment - inside the room
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Ultrafiltration - High SEG
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Maintenance, manual cleaning and waste handling
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Laboratory activities
Manufacture
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Manufacture of substance
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Handle substance within a closed system.
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- With sample collection; Handle substance within a closed system.
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Transfer of substance or mixture (charging/discharging) at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Use of the substance within laboratory settings, including material transfers and equipment cleaning
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- site specific biological STP
- Application of site specific biological STP sludge on agricultural soil:
- yes
Conditions and measures related to external treatment of waste (including article waste)
- Particular considerations on the waste treatment operations:
- no
Other conditions affecting environmental exposure
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- wastewater
- Release estimation method:
- estimated release factor
- Remarks:
- 1
- Release from the site to::
- ambient air
- Release estimation method:
- estimated release factor
- Remarks:
- 0
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
- Remarks:
- 0
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Handle substance within a closed system.
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Handle substance within a closed system.
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Transfer of substance or mixture (charging/discharging) at dedicated facilities
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Exposure of workers
Exposure estimation
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- measured data
- Exposure estimation tool name:
- other: Use of the substance within laboratory settings, including material transfers and equipment cleaning
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
