Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 422-260-8 | CAS number: 45267-68-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Not known to be a direct inhalation hazard. If exposed to
dust, move to area of fresh air. Seek medical advice if
signs of discomfort.
Emergency measure - Eyes: Rinse immediately with plenty of water for at least 15
minutes. Seek medical attention if signs of discomfort.
Emergency measure - Skin: Wash with water and mild soap or detergent. If signs of
discomfort, seek medical attention. Remove contaminted
clothing and wash thoroughly before re-use.
Emergency measure - Ingestion: Do not induce vomiting. If ingestion has occurred within
the previous 5 minutes, administer small amounts of milk or
water (approx 160 ml, but less than 240 ml).
Seek medical advice if signs of discomfort. Show copy of
SDS or label to medical staff.
Fire-fighting measures
Recommended extinguishing agent: Dry foam, powder, water spray, carbon dioxide and other
extinguishing agents. No adverse reaction with normal
extinguishing agents is known. Evaluate the nature of the
incident before using water.
Product arising from burning: Complete combustion will lead to the formation of carbon
dioxide and water. Incomplete combustion (eg in enclosed
spaces) will result in volatile organic derivatives and
carbon monoxide.
The products of combustion are not considered to be
hazardous except in confined spaces.
Product determined by test: N
Protective equipment: Full protective equipment is recommended including breathing
apparatus, suitable gloves, goggles and face protection.
Precautions suitable for weak organic acids should be taken.
Accidental release measures
Emergency measures in case of spillage: Collect and place into correctly labelled containers and
dispose of as hazardous waste in accordance with local
regulations. Residues and minor spills may be washed away
with water to process drainage system if permitted under
local regulations.
Protective clothing should be worn including suitable eye
protection, gloves, coveralls and dust mask.
Handling and storage
Handling: Personal protective equipment applicable to a potential
irritant is required, such as rubber gloves, eye/face
protection and coveralls.
There is not considered to be a significant risk of
inhalation when used in an adequately ventilated area,
although precautions are recommended to avoid exposure.
Storage: The substance should be stored in the containers used for
supply, sealed under nitrogen to avoid oxidation. The
containers should be kept cool (< 25°C) to avoid melting.
Packaging of the substance and or preparation: Slurry transported in 200 litre drums or bulk containers
from site of synthesis for purification.
Purified solid transported in metal or fibre kegs with an
aluminium lining, containing up to 50 kg.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
Shippingopen allclose all
Special provisions / remarks
- Remarks:
- Transport: To be assessed once the classification and labelling for
supply has been confirmed by the competent authority.
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Danger other than fire: Avoid contact with strong oxidising and reducing agents.
Chemical reaction with water: The substance does not react violently with water.
Dust explosion: As with other organic solids, there is a possibility of dust
explosion. As a precaution, it is recommended that levels
of dust are kept low and equipment is suitably earthed to
prevent electrostatic discharge.
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: The substance is not consumed during use. The preparation
cannot be recycled and any unused material should be
destroyed.
Industry - Possibility of neutralisation: As a weak organic acid, saponification with suitable strong
base will reduce the potential irritancy of the substance.
Industry - Possibility of destruction: controlled discharge: Not recommended, although suitable treatment methods will
ensure breakdown of the susbtance.
Industry - Possibility of destruction - incineration: This is recommended for large quantites and solvent wastes.
Closed system incinerators with scrubbers should be used in
compliance with local and national legislation.
Industry - Possibility of destruction - water purification: A combination of chemical, physical and biological processes
will remove the substance from water.
Industry - Possibility of destruction - other: No other recommended methods of disposal.
Public at large - Possibility of recovery/recycling: Not applicable to the general public.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.