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EC number: 232-453-7
CAS number: 8032-32-4
A complex combination of hydrocarbons obtained by the fractional distillation of petroleum. This fraction boils in a range of approximately 20°C to 135°C (58°F to 275°F).
Unleaded gasoline was examined for its chronic dermal
toxicity potential. Unleaded gasoline was administered via dermal
application to the skin of 50 Swiss mice three times per week for two
years. A negative control group was not treated while the two positive
control groups were administered 0.05 ml of 0.05% BaP and 0.05 ml of
0.15% BaP in acetone. The test substance caused hyperkeratosis, fibrosis
of the dermis, extoabscess and skin ulceration in the treatment areas.
The incidence of skin carcinomas, liver hemangiomas, lung adenomas, and
malignant lymphomas was no greater with the test substance than for the
negative control group. Unleaded gasoline did not display chronic
dermal toxicant properties in this study. This finding
does not warrant the classification of unleaded gasoline as a chronic
dermal toxicant under Regulation (EC) 1272/2008 on classification,
labeling, and packaging of substances and mixtures (CLP) or under the
Directive 67/518/EEC for dangerous substances and Directive 1999/45/EC
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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