Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: no test data just read-across

Data source

Referenceopen allclose all

Reference Type:
other: QSAR
Title:
Unnamed
Year:
2012
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
no guideline followed
Guideline:
other: read-across
GLP compliance:
no
Test type:
other: read-across

Test material

Constituent 1
Reference substance name:
methyltio 2-(acetyloxy) propionate
IUPAC Name:
methyltio 2-(acetyloxy) propionate
Constituent 2
Reference substance name:
methyltio 2(propionyloxy) propionate
IUPAC Name:
methyltio 2(propionyloxy) propionate

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 006 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Toxicity Category IV
Remarks:
Migrated information H302 Criteria used for interpretation of results: EU
Conclusions:
Predicted oral LD50 value in the rat 1006 mg/kg
Executive summary:

Predicted oral LD50 value in the rat 1006 mg/kg