Registration Dossier
Registration Dossier
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EC number: 231-626-4 | CAS number: 7659-86-1
Carcinogenicity
Administrative data
Description of key information
There is no available study on the chronic toxicity and carcinogenicity of 2-ethylhexyl thioglycolate. However, results from a subacute study indicate that 2-EHTG does not cause any significant systemic toxicity resulting from prolonged exposure. The consistently negative results from the series of genotoxicity tests (in vitro gene mutations assays on bacteria (Ames test) and mammalian cells (mouse lymphoma assay) and a micronucleus test with mice) do not suggest any cause for concern with respect to carcinogenicity. In addition, 2- EHTG are expected to be initially hydrolysed in several tissues by carboxylesterases to thioglycolic acid and corresponding alcohols (2-ethylhexanol). 2-ethylhexanol is not considered as carcinogenic compound.
Key value for chemical safety assessment
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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