Registration Dossier
Registration Dossier
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EC number: 231-710-0 | CAS number: 7695-91-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
The respiration rate of microorganisms in presence of DL-Alpha-Tocopheryl acetate was tested by a oxygen consumption test according to ROBRA focusing on the respiration of Pseudomonas putida. After 30 minutes an EC50 > 10000 mg/l was determined (BASF AG, 1991). Changes in the respiration rate of activated sludge as induced by DL-Alpha-Tocopheryl acetate were studied in a test performed in compliance with ISO 8192. An EC20 > 927 mg/l was determined after an inoculation time of 30 minutes.
As EC50 values are used as the basis for the calculation of a PNECstp, the study with Pseudomonas putida (BASF AG, 1991) is selected as key study.
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