Registration Dossier
Registration Dossier
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EC number: 244-017-3 | CAS number: 20769-85-1
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
2 in-vitro tests have shown that 2-bromoisobutyryl bromide induced mutation in salmonella tymphimurium and chromosomal aberrations in cultured human peripheral blood lymphocytes. An in-vivo test has confirmed that 2-bromoisobutyryl bromide induced micronuclei in the bone marrow of treated mice.
Short description of key information:
2-bromoisobutyryl bromide has to be considered as mutagen since 3 experimental studies carried on the topic conclude in the presence of this risk..
Endpoint Conclusion: Adverse effect observed (positive)
Justification for classification or non-classification
2-bromoisobutyryl bromide has to be considered as Mutagen. The hazard statement Mutagen cat.1B and the sentence H340 "May cause genetic defects" are then required.
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