Registration Dossier
Registration Dossier
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EC number: 271-653-9 | CAS number: 68603-38-3 This substance is identified by SDA Substance Name: C16-C18 and C18 unsaturated alkyl carboxylic acid amide diethanol and SDA Reporting Number: 11-024-00.
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Based on a guideline compliant study conducted with amides, C16-18 (even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl) in Scenedesmus subspicatus, the 24 -72 h ErC50 was determined to be 18.6 mg/L. Further, the 72 h EbC50 was 23.4 mg/L and the NOEC was 2.0 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 18.6 mg/L
- EC10 or NOEC for freshwater algae:
- 2 mg/L
Additional information
A study was conducted to determine the toxicity of amides, C16-18 (even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl) toScenedesmus subspicatusaccording to EU Method C.3. Algae were exposed to the test substance for 72 hours at 0, 0.5, 1.0, 2.0, 4.0, 8.0, 16.0 and 32.0 mg/L in a static system. Biomass and growth rate were determined. Under the conditions of the study, the 24 -72 h ErC50of the test substance forScenedesmus subspicatus, based on nominal concentrations, was 18.6 mg/L. The 72 h EbC50was 23.4 mg/L and the NOEC was 2.0 mg/L (Scholz, 1991).
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