Registration Dossier
Registration Dossier
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EC number: 205-440-9 | CAS number: 140-90-9
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data from review document on related substance to strengthen read-across for other endpoints
Original reference not found
Methods and details of results not described in detail, but were clearly considered acceptable for the Australian Government review
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- CCOHS, Registry of Toxic Effects of Chemical Substances, updated July 2010,
- Author:
- CCOHS, Registry of Toxic Effects of Chemical Substances
- Year:
- 2 010
- Bibliographic source:
- www.ccohs.ca
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Izmerov, N.F.et all
- Year:
- 1 982
- Bibliographic source:
- Moscow, Centr of International Projects, GKNT, vol.102
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Remarks:
- Original 1982 study thought to pre-date universal GLP
- Test type:
- traditional method
- Limit test:
- no
Test material
- Reference substance name:
- Potassium O-butyl dithiocarbonate
- EC Number:
- 212-808-2
- EC Name:
- Potassium O-butyl dithiocarbonate
- Cas Number:
- 871-58-9
- IUPAC Name:
- potassium O-butyl dithiocarbonate
- Reference substance name:
- Potassium n-butyl xanthate
- IUPAC Name:
- Potassium n-butyl xanthate
- Test material form:
- not specified
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 2 h
- Control animals:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LC50
- Effect level:
- 7 690 mg/m³ air
- Clinical signs:
- other: Not specified in secondary source
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Remarks:
- Not considered acutely toxic by inhalation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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