Registration Dossier
Registration Dossier
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EC number: 450-050-6 | CAS number: -
Guidance on Safe Use
Guidance on Safe Use
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Administrative data
First-aid measures
Emergency measure - Inhalation: Move to fresh air. Consult a physician if irritating
symptoms develop and persist.
Emergency measure - Eyes: Rinse immediately with gently running water for 15 minutes,
maintaining eyelids open. Consult an ophthalmologist or a
physician.
Emergency measure - Skin: Rinse contaminated skin immediately with plenty of water.
Emergency measure - Ingestion: If feeling sick consult a physician.
symptoms develop and persist.
Emergency measure - Eyes: Rinse immediately with gently running water for 15 minutes,
maintaining eyelids open. Consult an ophthalmologist or a
physician.
Emergency measure - Skin: Rinse contaminated skin immediately with plenty of water.
Emergency measure - Ingestion: If feeling sick consult a physician.
Fire-fighting measures
Recommended extinguishing agent: Water, foam & dry powder
Product arising from burning: Carbon oxides and Nitrogen oxides.
Product determined by test: N
Protective equipment: The on-site fire crews would tackle any localized fire with
a dry powder extinguisher. If a major fire was involved, the
foam enhanced building sprinkler system would automatically
activate. The building drainage system is arranged such
that all fire water run off is captured within a 200m3
catchment tank. The contents of the tank would be analyzed
and if required, all of the liquid would be sent for
incineration. If there is a risk of fume inhalation, the
firemen would wear a Kappler responder gas-tight suit (to
standard ASTM F1001 chemical test battery and ASTMF739
Permeation test).
Product arising from burning: Carbon oxides and Nitrogen oxides.
Product determined by test: N
Protective equipment: The on-site fire crews would tackle any localized fire with
a dry powder extinguisher. If a major fire was involved, the
foam enhanced building sprinkler system would automatically
activate. The building drainage system is arranged such
that all fire water run off is captured within a 200m3
catchment tank. The contents of the tank would be analyzed
and if required, all of the liquid would be sent for
incineration. If there is a risk of fume inhalation, the
firemen would wear a Kappler responder gas-tight suit (to
standard ASTM F1001 chemical test battery and ASTMF739
Permeation test).
Accidental release measures
Emergency measures in case of spillage: In the event of spillage, the solid will be contained by the
use of adsorbent 'pigs' and the use of loose adsorbent
vermiculite. Drainage covers would be blanked off and the
residues would be wiped, scraped and vacuumed up. All such
collections of spilt waste would be securely contained and
set for incineration.
use of adsorbent 'pigs' and the use of loose adsorbent
vermiculite. Drainage covers would be blanked off and the
residues would be wiped, scraped and vacuumed up. All such
collections of spilt waste would be securely contained and
set for incineration.
Handling and storage
Handling: During the sampling process in the QA Dept., the sampler
will wear a Tyvek suit (EN 369/374-3), nitrile gloves (EN388
& EN 374), and a Kemira respirator (EN 12941/2).
During charging, the intermediate vessel is equipped with
local exhaust ventilation. Ventilation rates are checked to
ensure adequate air flow and hence good levels of
containment and control.
The mode of transfer to the reactor is by means of an
intermediate bin hoist so that the material is charged to
the reactor on dispensation within an enclosed system.
During the charging operation the operator will wear a Tyvek
suit (EN 369/374-3), nitrile gloves (EN388 & EN 374), and a
Tornado Air pack (filter tested in line with EN 149:2001).
All operators are trained regarding the hazards associated
with the process - this training is given by the process
chemist prior to the start of the campaign. They are also
given general training on the Control of Substances
Hazardous to Health (COSHH) Regulations and PPE awareness
training. This training is an important administrative
control.
Storage: The enclosed substance will be stored under cover in a
warehouse until required for use in the production building.
Only the required amount or one batch will be transferred
to the production building at any one time.
Packaging of the substance and or preparation: The substance will be supplied in 50kg fibreboard kegs with
inner polyethylene liners.
will wear a Tyvek suit (EN 369/374-3), nitrile gloves (EN388
& EN 374), and a Kemira respirator (EN 12941/2).
During charging, the intermediate vessel is equipped with
local exhaust ventilation. Ventilation rates are checked to
ensure adequate air flow and hence good levels of
containment and control.
The mode of transfer to the reactor is by means of an
intermediate bin hoist so that the material is charged to
the reactor on dispensation within an enclosed system.
During the charging operation the operator will wear a Tyvek
suit (EN 369/374-3), nitrile gloves (EN388 & EN 374), and a
Tornado Air pack (filter tested in line with EN 149:2001).
All operators are trained regarding the hazards associated
with the process - this training is given by the process
chemist prior to the start of the campaign. They are also
given general training on the Control of Substances
Hazardous to Health (COSHH) Regulations and PPE awareness
training. This training is an important administrative
control.
Storage: The enclosed substance will be stored under cover in a
warehouse until required for use in the production building.
Only the required amount or one batch will be transferred
to the production building at any one time.
Packaging of the substance and or preparation: The substance will be supplied in 50kg fibreboard kegs with
inner polyethylene liners.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport: Regulations Class UN No. PGr.
RID/ADR: 8/C8 3263 III LQ: LQ24
ICAO/IATA-DGR: 8/ 3263 III
GGVSee/IMDG-Code:8/ 3263 III LQ:2Kg
Proper Shipping name: Corrosive solid, basic, organic,
n.o.s. Class 8(contains: Adamantane derivative)
IMDG-Code: EMS No. 8-15
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Danger other than fire: None known.
Chemical reaction with water: No.
Dust explosion: Data not known.
Dust explosion determined by test: N
Chemical reaction with water: No.
Dust explosion: Data not known.
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: Since it is envisaged that most of the notifiable substance
will be consumed in the process, recovery is not
applicable.
Industry - Possibility of neutralisation: The substance is a primary amine and therefore basic in
chemical nature. It can be chemically neutralized by the
addition of a mineral acid e.g. hydrochloric acid to produce
the hydrochloride salt. This mode of neutralization would
not be attempted.
Industry - Possibility of destruction: controlled discharge: All process effluent will be contained, not allowed to enter
the environment and will be sent for incineration within
the UK.
Industry - Possibility of destruction - incineration: All process effluent will be contained, not allowed to enter
the environment and will be sent for incineration within
the UK.
Industry - Possibility of destruction - water purification: Not applicable.
Industry - Possibility of destruction - other: Not applicable.
Public at large - Possibility of recovery/recycling: Not applicable.
Public at large - Possibility of neutralisation: Not applicable.
Public at large - Possibility of destruction: controlled discharge: Not applicable.
Public at large - Possibility of destruction - incineration: Not applicable.
Public at large - Possibility of destruction - water purification: Not applicable.
Public at large - Possibility of destruction - others: Not applicable.
will be consumed in the process, recovery is not
applicable.
Industry - Possibility of neutralisation: The substance is a primary amine and therefore basic in
chemical nature. It can be chemically neutralized by the
addition of a mineral acid e.g. hydrochloric acid to produce
the hydrochloride salt. This mode of neutralization would
not be attempted.
Industry - Possibility of destruction: controlled discharge: All process effluent will be contained, not allowed to enter
the environment and will be sent for incineration within
the UK.
Industry - Possibility of destruction - incineration: All process effluent will be contained, not allowed to enter
the environment and will be sent for incineration within
the UK.
Industry - Possibility of destruction - water purification: Not applicable.
Industry - Possibility of destruction - other: Not applicable.
Public at large - Possibility of recovery/recycling: Not applicable.
Public at large - Possibility of neutralisation: Not applicable.
Public at large - Possibility of destruction: controlled discharge: Not applicable.
Public at large - Possibility of destruction - incineration: Not applicable.
Public at large - Possibility of destruction - water purification: Not applicable.
Public at large - Possibility of destruction - others: Not applicable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
