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EC number: 293-026-9 | CAS number: 91050-80-5
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to terrestrial arthropods.
Key value for chemical safety assessment
Additional information
In accordance with Regulation (EC) No. 1907/2006, Annex IX, 9.4, column 2, further studies on the effects on terrestrial organisms do not have to be conducted since the chemical safety assessment indicates that there is no need. No experimental data on toxicity to terrestrial arthropods are available for Fatty acids, C16-18, tetraesters with 3,3'-oxybis[1,2-propanediol] (CAS 91050-80-5). The test substance is characterised by a high log Koc (log Koc > 5) indicating a considerable potential for adsorption to the soil particles. Therefore, tests with soil-dwelling organisms that feed on soil particles are most relevant for the evaluation of soil toxicity of Fatty acids, C16-18, tetraesters with 3,3'-oxybis[1,2-propanediol]. Thus, no higher toxicity is expected for terrestrial arthropods in comparison to soil macroorganisms.
Read-across in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 from the structurally related analogue substance 1,2,3 -propanetriol, homopolymer, diisooctadecanoate (CAS 63705-03-3) did show effects on reproduction for earthworms in an chronic test according to OECD 222 (NOEC (56d) = 250 mg/kg soil dw).
Testing the toxicity on earthworm evaluates the exposure to the test substance via soil pore water, surface contact as well as by ingestion of soil particles. This is of particular importance as one should focus on the pathway of exposure (ECHA, 2012). Thus, it can be assumed that earthworms would be highly exposed to toxicants in soil and hence are most sensitive to the potential adverse effects of the substance. In accordance with Regulation (EC) No. 1907/2006, Annex IX, Column 2, 9.4 further studies on the effects on terrestrial invertebrates do not have to be conducted since the chemical safety assessment indicates that toxicity to terrestrial arthropods is not expected to be of concern.
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