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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
1994
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not GLP and not enough details to consider it a ful describe study. It is scientiffivally valid to assess the endpoint

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EPA OPPTS 870.1200 (Acute Dermal Toxicity)
Deviations:
no
GLP compliance:
not specified
Test type:
fixed dose procedure
Limit test:
yes

Test material

Constituent 1
Reference substance name:
Fatty acids, C6-C12 methyl esters
IUPAC Name:
Fatty acids, C6-C12 methyl esters
Details on test material:
Purity : 99.6%

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Doses:
2000 mg/kg
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
the substance was not considered to be an acute dermal toxic
Executive summary:

LD 50 has been tested in a fixed dose test at 2000 mg/kg bw on rabbit with fatty acids C6 -C12 methyl esters following EPA OPPTS 870.1200 with no sigh of toxicity.