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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Sources are collections of data in handbooks, review articles or official reports.

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Handbook of Environmental Data on Organic Chemicals, 4th Edition
Author:
Verschueren K
Year:
2001
Bibliographic source:
John Wiley & Sons
Reference Type:
review article or handbook
Title:
Dimethylformamide, SIDS Initial Assessment Report For SIAM 13
Author:
OECD
Year:
2001
Bibliographic source:
UNEP PUBLICATIONS
Reference Type:
review article or handbook
Title:
N,N-DIMETHYLFORMAMIDE
Author:
Lewis M., G. Long and M.E. Meek
Year:
2001
Bibliographic source:
Concise International Chemical Assessment Document 31
Reference Type:
review article or handbook
Title:
CHRONIC TOXICITY SUMMARY N,N-DIMETHYLFORMAMIDE
Author:
Canadian Office of Environmental Health Hazard Assessment (OEHHA)
Year:
2000
Bibliographic source:
http://oehha.ca.gov/air/chronic_rels/pdf/68122.pdf

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No data available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N-dimethylformamide
EC Number:
200-679-5
EC Name:
N,N-dimethylformamide
Cas Number:
68-12-2
Molecular formula:
C3H7NO
IUPAC Name:
N,N-dimethylformamide
Test material form:
not specified

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
3.8 hPa
Remarks on result:
other: Verschueren, 2001: 22.7 mm at 20°C; 3.8 hPa at 20°C; 13.4 hPa at 40°C
Temp.:
20 °C
Vapour pressure:
3.5 hPa
Remarks on result:
other: Original source of the value used in the SIDS Report: IPCS (International Programme on Chemical Safety), Environmental Health Criteria 114, World Health Organization (WHO), Geneva, 1991
Temp.:
25 °C
Vapour pressure:
490 Pa
Remarks on result:
other: Lewis M., G. Long and M.E. Meek, 2001; Original source: Riddick JA, Bunger WB, Sakano TK (1986) Techniques of chemistry, 4th ed. Vol. II. Organic solvents. Properties and methods of purification. New York, NY, John Wiley & Sons, pp. 656; 1089–1091.
Temp.:
25 °C
Vapour pressure:
3.7 Torr
Remarks on result:
other: Source is OEHHA: value of 3.7 torr corresponds with 490 Pa.

Any other information on results incl. tables

DMF is infinitely miscible with water and its vapour pressure is lower than that of water. It can be assumed that DMF shows very little tendency to evaporate from aqueous solutions.

Applicant's summary and conclusion

Conclusions:
Based on public data, the average vapour pressure of DMF (CAS no. 68-12-2) is 365 Pa at 20 °C or 490 Pa at 25 °C.