Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 607-485-3 | CAS number: 25015-63-8
Endpoint summary
Administrative data
Description of key information
Additional information
With high probability acutely not harmful to aquatic organisms.
This aquatic toxicity assessment was based on the following data:
The test substance is known to rapidly hydrolyse in aquatic systems forming Pinacol (CAS 76-09-5), boric acid (CAS 10043-35-3, no legal classification environment) and elemental hydrogen (H2).
Fish: The toxicity of the hydrolysis product boric acid was investigated in a study published in 1977 (Birge & Black 1977). In this study, the LC50 (7d) on the development of fish larvae (Carassius auratus) was found to be 260 mg/L (referring to elemental boron). Furthermore, a QSAR calculation using ECOSAR v1.11 for the hydrolysis product Pinacol revealed an estimated LC50 (96h) value of ca. 1977 mg/L on fish (BASF SE, 2013). The result of this calculation is considered to be valid due to the simple molecular structure of the hydrolysis product Pinacol. Based on these values, the test substance and its products of hydolysis are not considered to be acutely harmful to fish.
Aquatic invertebrates: The toxicity of the hydrolysis product boric acid was investigated in study published in 1984 (ECB IUCLID 2000). In this study, the LC50 (48h) on Daphnia magna was found to be 760 mg/L. Furthermore, a QSAR calculation using ECOSAR v1.11 for the hydrolysis product Pinacol revealed an estimated EC50 (48h) value of ca. 981 mg/L on daphnids (BASF SE, 2013). The result of this calculation is considered to be valid due to the simple molecular structure of the hydrolysis product Pinacol. Based on these values, the test substance and its products of hydolysis are not considered to be acutely harmful to aquatic invertebrates.
Aquatic Algae: No reliable experimental data for the assessment of the toxicity to algae are currently available. Hence, a QSAR calculation using ECOSAR v1.11 for the hydrolysis product Pinacol revealed an estimated EC50 (96h) value of ca. 419 mg/L on fish (BASF SE, 2013). The ChV-value was estimated to be ca. 81 mg/L. The results of this calculation are considered to be valid due to the simple molecular structure of the hydrolysis product Pinacol. Based on these values, the test substance and its products of hydolysis are not considered to be acutely harmful to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
