Registration Dossier
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EC number: 482-220-0 | CAS number: 848301-69-9
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
OECD Test Guideline 207(Acute Toxicity Test with Eisenia foetida):
- LC50 (14-d): >1000 mg/kg dw test mat. (nominal) based on: mortality
- NOEC (14-d): ≥1000 mg/kg dw test mat. (nominal) based on: mortality
OECD Test Guideline 222 (Chronic Toxicity Test with Eisenia foetida):
- LC50 (4-w): >1000 mg/kg dw test mat. (nominal) based on: growth, reproduction and mortality
- NOEC (4-w): ≥1000 mg/kg dw test mat. (nominal) based on: growth, reproduction and mortality
Key value for chemical safety assessment
Additional information
A short-term earthworm toxicity study is available for the UVCB substance GTL Base Oil Distillates. The test was conducted in accordance with OECD 207 and GLP. Earthworms (Eisenia foetida) were exposed to a single concentration of the substance at a nominal loading rate of 1000 mg/kg of soil (dry weight) for a period of 14 days in artificial soil. There were no significant mortalities or sub-lethal effects during the 14-day exposure period. The 14-d acute LC50for earthworms was therefore determined to be greater than 1000 mg/kg dw.
A long-term toxicity study with E. foetida has been conducted with GTL Base Oil Distillates in accordance with GLP and OECD 222. Adult test organisms were exposed to 10, 32, 100, 320 and 1000 mg/kg dw soil for 4 weeks and then removed, while the juvenile earthworms remained in the vessels for an additional 4 weeks. Adult mortality and mean change in body weight were recorded, as well as mean reproduction rate of juveniles. Based on these parameters an LC50and a LOEC could not be determined and a NOEC of at least 1000 mg/kg dw has been determined.
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