Registration Dossier
Registration Dossier
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EC number: 235-730-0 | CAS number: 12627-14-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) > 800 mg/L (Daphnia magna), lithium silicate solution; equivalent to > 220 mg active matter/L
However, for the purpose of risk assessment and as explained in the section on the calculation of Predicted No Effect Concentrations, the PNEC is derived from the ubiquitous SiO2 background concentration in freshwater in Europe, which is 7.5 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 220 mg/L
Additional information
In a non-GLP study by Häner (1998) following OECD Guideline 202, static exposure of the freshwater cladoceran Daphnia magna to silicic acid, lithium salt (aqueous solution, MR 4.05, solid content 27.5%) was tested at concentrations of 50, 100, 200, 400 and 800 mg/L nominal (test material, at pH 6.2 -7.8), and resulted in a 48 h-EC50 of > 800 mg/L (nominal, test material), equivalent to > 220 mg active matter/L. An EC0 was calculated as 213 mg/L (nominal, test material), equivalent to 58.56 mg active matter/L, after 48 h.
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