Registration Dossier
Registration Dossier
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EC number: 607-145-4 | CAS number: 227197-72-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 6-Chlorobenzoxazol
- IUPAC Name:
- 6-Chlorobenzoxazol
- Reference substance name:
- 6-chloro-1,3-benzoxazole
- EC Number:
- 607-145-4
- Cas Number:
- 227197-72-0
- Molecular formula:
- C7H4ClNO
- IUPAC Name:
- 6-chloro-1,3-benzoxazole
- Details on test material:
- Purity: 98.6 % GC(a/a)
Constituent 1
Constituent 2
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Vehicle:
- unchanged (no vehicle)
- Duration of treatment / exposure:
- 24h
- Observation period (in vivo):
- 7d
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Testing of 6-Chlorobenzoxazole for primary eye irritation in the rabbit showed that the substance is not irritating to eyes according to the classification criteria of directive 93/21/EEC.
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