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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: testing method performed according to OECD107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
4'-ethoxy-3-hydroxy-2-naphthanilide
EC Number:
225-200-7
EC Name:
4'-ethoxy-3-hydroxy-2-naphthanilide
Cas Number:
4711-68-6
Molecular formula:
C19H17NO3
IUPAC Name:
N-(4-ethoxyphenyl)-3-hydroxy-2-naphthamide

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.8
Temp.:
23 °C
pH:
ca. 7

Any other information on results incl. tables

Table 1: Results in detail

determ. no.

   stock solution [ml]    n-octanol [ml]     test substance conc. in n-octanol phase [mg/l]     test substance conc. in water phase [mg/l]  log Pow   
  A1    5   10  661,4  0,62  3,0
  A2    5   10  638,9  1,17  2,7
  B1   10   10  634,6  1,14  2,7
  B2   10   10  653,5  0,97  2,8
  C1   20   10  657,2  1,31  2,7
  C2   20   10  646,2  1,42  2,7

mean

   ---   ---   ---   ---  2,8

Stock solution: 722 mg/l

Conc. of filtered stock solution: 665 mg/l

Applicant's summary and conclusion

Conclusions:
Due to the partition coefficient n-octanol-water bioaccumulation is not expected.