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Diss Factsheets
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EC number: 244-870-1 | CAS number: 22252-43-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Flammability
Administrative data
- Endpoint:
- flammable solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 January 2010 – 01 April 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.10 (Flammability (Solids))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Part III: Classification Procedures, Test Methods and Criteria Relating to Explosives of Class 3, Class 4, Division 5.1 and Class 9, Test N.1: 2003
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- EC Number:
- 244-870-1
- EC Name:
- (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Cas Number:
- 22252-43-3
- Molecular formula:
- C8H10N2O3S
- IUPAC Name:
- 7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Details on test material:
- - Name of test material (as cited in study report): 7-ADCA
- Molecular formula: C8H10N2O3S
- Molecular weight: 214.2
- Substance type: White powder
- Physical state: solid
- Analytical purity: 99.0%
- Impurities: -
- Isomers composition: -
- Purity test date: -
- Lot/batch No: D212013
- Expiration date of the lot/batch: 28 February 2011 (retest date)
- Stability under test conditions: Stable
- Storage condition of test material: In refrigerator (2-8°C) in the dark
- Other: Test substance handling: -
Constituent 1
Results and discussion
Pyrophoric solids
- Test procedure:
- ignition time on contact with air
- Remarks:
- Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).
- Remarks on result:
- no ignition on contact with air (not further specified)
- Remarks:
- corresponding to 'no' in migrated source record.
Pyrophoric liquids
- Test procedure:
- ignition time on contact with air
- Remarks:
- Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).
- Remarks on result:
- no ignition on contact with air (not further specified)
- Remarks:
- corresponding to 'no' in migrated source record.
Any other information on results incl. tables
The flame of the gas burner did ignite the test substance pile. The test substance burned with a red/orange flame and turned into a charred residue. After removal of the ignition source, the flame extinguished immediately and no propagation of combustion was observed.
Applicant's summary and conclusion
- Interpretation of results:
- non flammable
- Remarks:
- Migrated information
- Conclusions:
- The preliminary screening test was performed for the determination of the flammability of 7-ADCA. No propagation of combustion of the test substance along 200 mm length of the pile within 4 minutes was observed. According to the guidelines performance of the burning rate test is not required. Based on the results obtained the test substance is considered ‘not highly flammable’.
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