Registration Dossier

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
3 (not reliable)

Data source

Reference
Reference Type:
review article or handbook
Title:
Irritation / Corrosion study
Author:
Marhold J
Year:
1986
Bibliographic source:
Marhold J., Prehled prumyslove toxikologie: Organicke latky, Avicenum, prague, Czechoslovakia, p. 1058 (1986)

Materials and methods

Principles of method if other than guideline:
Database entry.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-5-hydroxynaphthalene-2,7-disulphonic acid
EC Number:
201-975-7
EC Name:
4-amino-5-hydroxynaphthalene-2,7-disulphonic acid
Cas Number:
90-20-0
Molecular formula:
C10H9NO7S2
IUPAC Name:
4-amino-5-hydroxynaphthalene-2,7-disulfonic acid
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified

Results and discussion

In vivo

Results
Remarks on result:
other: 500 mg/24h

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Not enough data for classification.