Registration Dossier
Registration Dossier
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EC number: 909-152-0 | CAS number: -
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: non-GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Guideline:
- other: The experimental procedure followed is outlined in the Study Report attached
- GLP compliance:
- no
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- β,1,1,2,3,3-hexamethylindan-5-ethanol
- EC Number:
- 214-934-3
- EC Name:
- β,1,1,2,3,3-hexamethylindan-5-ethanol
- Cas Number:
- 1217-08-9
- Molecular formula:
- C17H26O
- IUPAC Name:
- 2-(1,1,2,3,3-pentamethyl-2,3-dihydro-1H-inden-5-yl)propan-1-ol
- Details on test material:
- Study material (CAS #1217-18-9) referred to as Substance 78-004-c in the Study report
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- ethanol
- Control animals:
- yes
Results and discussion
Effect levelsopen allclose all
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 10 other: g/kg
- Based on:
- test mat.
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 33.1 other: g/kg
- Based on:
- test mat.
- Remarks on result:
- other: vehicle Control
- Mortality:
- No deaths occurred in any animals in either Group I (78-004-c) or in Group II (78-004-e)
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information
- Conclusions:
- Dermal LD50 of the test substance, 78-004-c, is considered to be greater than 10.0 g/kg, while the vehicle control Dermal LD50, 78-004-e, is greater than 33.1 g/kg.
- Executive summary:
Dermal LD50 of the test substance, 78-004-c, is considered to be greater than 10.0 g/kg, while the vehicle control Dermal LD50, 78-004-e, is greater than 33.1 g/kg.
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