Registration Dossier
Registration Dossier
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EC number: 202-452-6 | CAS number: 95-79-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Original Report not available.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
Materials and methods
Test guideline
- Guideline:
- other: no data
- GLP compliance:
- no
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- 5-chloro-o-toluidine
- EC Number:
- 202-452-6
- EC Name:
- 5-chloro-o-toluidine
- Cas Number:
- 95-79-4
- Molecular formula:
- C7H8ClN
- IUPAC Name:
- 5-chloro-2-methylaniline
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- other: sesame oil
Results and discussion
Effect levelsopen allclose all
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 716 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- >= 646 - <= 793
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 632 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- >= 551 - <= 726
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
