Registration Dossier
Registration Dossier
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EC number: 200-741-1 | CAS number: 70-55-3
Toxicity to birds
Administrative data
- Endpoint:
- short-term toxicity to birds: acute oral toxicity test
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only a short summary on the method is given and only final endpoints are given.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- The acute oral toxicity of 369 pesticidal, pharmaceutical and other chemicals to wild birds
- Author:
- Schafer, E. W.
- Year:
- 1 972
- Bibliographic source:
- Toxicology and applied pharmacology 21, p. 315-330 (1972)
- Reference Type:
- publication
- Title:
- The acute oral toxicity repellency, and hazard potential of 998 chemicals to one or more species of wild and domestic birds
- Author:
- Schafer, E. W., Bowles, W. A. and Hurlbut, J.
- Year:
- 1 983
- Bibliographic source:
- Arch. of Environmental contamination and toxicology 12, p. 355-382 (1983)
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Wild-trapped birdds preconditioned to captivity for 2-6 weeks were dosed by gavage with solutions or susmensions of the test chemical in propylene glycol. LD50 values were calculated.
- GLP compliance:
- no
Test material
- Reference substance name:
- Toluene-4-sulphonamide
- EC Number:
- 200-741-1
- EC Name:
- Toluene-4-sulphonamide
- Cas Number:
- 70-55-3
- Molecular formula:
- C7H9NO2S
- IUPAC Name:
- 4-methylbenzene-1-sulfonamide
Constituent 1
- Dose method:
- gavage
- Analytical monitoring:
- no
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- other: Agelaius phoeniceus (red-winged blackbird), Sturnus vulgaris (starling)
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 75 mg/kg bw
- Conc. / dose based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: for both bird species
- Repellency factors (if applicable):
- Red-winged blackbird:
R50 (%) = 0.680
R50 (mg/kg) = 52.3; assuming 50% consumption of an average food intake during one feeding session (1.00 g) and an average body weight of 65 g.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
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