Registration Dossier
Registration Dossier
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EC number: 201-475-9 | CAS number: 83-42-1
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- 1-Chlor-2-methyl-3-nitrobenzol (2-Chlor-6-nitrotoluol) BUA Stoffbericht 61
- Author:
- Beratergremium für umweltrelevante Altstoffe (BUA)
- Year:
- 1 991
- Bibliographic source:
- VCH Verlagsgesellschaft mbH, Weinheim, ISBN 3-527-28427-3
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 983
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-chloro-6-nitrotoluene
- EC Number:
- 201-475-9
- EC Name:
- 2-chloro-6-nitrotoluene
- Cas Number:
- 83-42-1
- Molecular formula:
- C7H6ClNO2
- IUPAC Name:
- 1-chloro-2-methyl-3-nitrobenzene
Constituent 1
Test animals
- Species:
- rabbit
Test system
- Type of coverage:
- semiocclusive
- Duration of treatment / exposure:
- 4 h
- Observation period:
- 72 h
Results and discussion
Any other information on results incl. tables
The investigation showed slight irritation in the form of mild to significant erythema, in individual cases visible even after 72 hours,
but no edema.Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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