Registration Dossier
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EC number: 255-901-3 | CAS number: 42594-17-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
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- pH
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- Nanomaterial surface chemistry
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- Nanomaterial pour density
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates β in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
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- Toxicological Summary
- Toxicokinetics, metabolism and distribution
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
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- Specific investigations
- Exposure related observations in humans
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- Additional toxicological data

Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
According to Table R.7.11-2, Chapter R.7c of the ECHA Guidance on information requirements and chemical safety assessment (version 2.0, November 2014), substances with a log Kow>5 and EC/LC50>1 mg/L (no toxicity at the highest loading rate tested (100 mg/L) on fish, aquatic invertebrates and algae for the registered substance), have to be assigned in soil category 3. As mentioned in Table R.7.11 -2, the approach for screening assessment of the terrestrial hazard in this soil category is to evaluate the risk based on EPM and to conduct a confirmatory long-term soil toxicity testing with the most sensitive organism identified in the aquatic toxicity data.
Likewise,according to the section R.7.11.5.3., Chapter R.7c of the ECHA Guidance on information requirements and chemical safety assessment (version 2.0, November 2014), βthe data required should cover not just different taxa but also different pathways of exposure (e.g. feeding, surface contact), and this should be taken into account when deciding on the adequacy and relevance of the data. Thus earthworm testing allows potential uptake via each of surface contact, soil particle ingestion and porewater, while plant exposure will be largely via porewater.β.
Therefore, the test substance being assigned in soil category 3, the registrant proposes to evaluate the risk based on EPM and to perform a long-term test on soil earthworm according to the OECD 222 testing guideline. This test will be carried out concurrently with the aquatic bioaccumulation test.
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