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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

OECD 202 study conducted under GLP

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Additional information

The acute toxicity of Methyl n-amyl Ketone to Daphnia magna was determined in a 48-hour, semi-static, aquatic effects test. The test was conducted with five concentrations up to 100 mg/L (nominal), 90.1 mg/L (mean measured). There was no immobilization observed at any test concentration throughout the exposure. The 48-hour EC50 value for Daphnia magna was estimated to be > 90.10 mg/L (mean measured), the highest concentration tested. The NOEC was determined to be 90.1 mg/L. As no effects were seen at the highest concentration tested, 100 mg/L nominal (mean measured = 90.1 mg/L) it is believed that the EC50 measured would be > 100 mg/L as well, therefore the nominal value is being used for the key value for the safety assessment.