Registration Dossier
Registration Dossier
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EC number: 701-365-5 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- None
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- > 551 g/L
- Temp.:
- 20 °C
- pH:
- ca. 4
- Details on results:
- Water solubility of the test item – experiments A to D
Experiment A B C D (blank)
Amount of test item (g) 12.76 12.74 12.76 --
Stirring time at 30 °C (h) 24 48 72 72
pH at 23 °C 3.9 4.0 3.9 6.5
aliquot of the flasks(g) 8.75 10.41 8.81 12.67
end weight after dilution(g) 24.84 24.91 24.81 24.92
Measured concentration (mg/l) 196.9 / 196.6 226.3 / 224.1 197.3 / 196.7 -- / --
Mean concentration (mg/l) 196.7 225.2 197.0 --
Water solubility (g/l) > 558.6 > 538.9 > 554.7 --
Average experiments A to C (without correction for the purity): > 550.7 g/l
Standard deviation: 10.4 g/l
Relative standard deviation: 1.9 %
Due to the high solubility of the test item it was impossible to get a saturated solution of the test item. Therefore not an exact value, but the range of the water solubility could be indicated for the test item. - Conclusions:
- Interpretation of results: very soluble (>10 g/L)
The water solubility for the test substance is found to be above 551 g/L at a temperature of 20 °C. - Executive summary:
The purpose of the study was determination of the water solubility cs of the test item according to the European Commission Regulation (EC) No.440/2008 Part A: methods of determination of physico –chemical properties. A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility.
The water solubility cS of the test item (without correction for purity) at a temperature of 20 °C is found to be greater than 551 g/L according to OECD guideline 105.
Reference
None
Description of key information
In a test conducted according to OECD guideline 105, the water solubility for the test substance is found to be >551 g/L at 20 °C.
Key value for chemical safety assessment
- Water solubility:
- 551 g/L
- at the temperature of:
- 20 °C
Additional information
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