[No public or meaningful name is available]

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is readily biodegradable

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Based on the results of the two guideline compliant read across biodegradation studies, the test substance, C12-14 TMAC, can be considered to be readily biodegradable.

Biodegradation in water:

readily biodegradable

Study 1:

A study was conducted to determine the biodegradability of the read across substance, Coco TMAC (34% Coco TMAC in water), according to OECD Guideline 310D (closed bottle test), in an aerobic activated sludge test system. The method was modified according to the recommendations of ECETOC (1985) or Bloket al.(1985). In the experiment, dark glass bottles of about 280 mL with glass stoppers were filled completely with a suspension of preconditioned activated sludge (3 mg s.s/L) in dilution water and a concentration of the test substance equivalent to about 6 mg ThOD (Theoretical Oxygen Demand)/L. The test was carried out in triplicate and, at every observation time, measurements of oxygen and pH were carried out in a new series of three bottles. The percentage degradation calculated based on measured BOD/COD values at 2, 4 and 6 weeks, were found to be 90%, 97% and 97% respectively. Based on the results, it was concluded that test substance passed the OECD criteria of 60% to classify it as readily biodegradable (Balk, 1987). Based on the results of the read across study, the test substance, C12-14 TMAC, can be considered to be readily biodegradable.

 

Study 2:

A study was conducted to determine the ready biodegradability of the read across substance, Coco TMAC, according to OECD Guideline 301D and EEC Guidelines using a closed bottle test. The test substance at 3 mg/L was incubated with sludge from activated sludge plant treating predominantly domestic waste and O2 consumption was determined over a period of 28 d. The biodegradation was calculated as the ratio of the biochemical oxygen demand to the theoretical oxygen demand. The test substance reached a biodegradation of 75% at Day 28. As evident from the biodegradation of 59% at Day 5 and 74% at Day 17, the plateau for ready biodegradability of the test substance was reached within 14 d of time point when 10% degradation occurred. Under the test conditions, the test substance was readily biodegradable (van Ginkel, 1989). Based on the results of the read across study, the test substance, C12-14 TMAC, can be considered to be readily biodegradable.