Registration Dossier
Registration Dossier
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EC number: 944-552-9 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The microbial inhibition of Liraglutide precursor is assumed to be comparable to that of the source substance S2 (MI3) because of the high degree of structural similarity:
• Liraglutide precursor and the source substance belong to the same chemical categories: human insulins, polypeptides and proteins
• Liraglutide precursor and the source substance are composed of polypeptide containing amino acids
The resulting EC50 values after 30 minutes and 180 minutes in the microbial inhibition study with the source substance S2 (MI3) were > 500 mg/L. Liraglutide precursor is predicted to have a toxicity to microorganisms with EC50 > 500 mg/L based on the results in the study with the source substance S2.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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