Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

The substance has low toxicity with no specific target organ identified.  Lithium is known to have neurological effects at relatively high concentrations, but at levels far greater than any accidental ingestion of the substance.

• There is no evidence of oral absorption and from coloured faecal excretion, it is likely a significant proportio passes through the GI tract unchanged. Results from in-vivo skin sensitisation testing suggests dermal penetration can occur.

• Thre is no evidence that the substance, or any similar-coloured metabolite, is excreted in urine

• Evidence from biodegradation testing and effect or S-9 activation suggests little if any metabolic degradation.

• Lithium and sodium ions are readily absorbed by ingestion and will be distributed in blood; as part of the natural ionic balance, excess sodium and lithium are excreted.

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential

Additional information