Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 800-181-3 | CAS number: 371756-75-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
Although there are no data available concerning the toxicity to microorganisms, the substance is considered with high probability acutely not harmful to microorganisms. Studies are available in order to determine the toxicity to microorganisms of four members of the category of derivatives of 4,4’-bis(1,3,5-triazinyl-2-yl)amino)stilbene-2,2’-disulfonic acid, each with one anilino and one alkyl amino moiety. All those studies demonstrate that the substances belonging to the category do not inhibit the activity of activated sludge (E(I)C > 100 mg/L).
EC 240-521-2: In a respiration rate study with domestic sewage sludge, the IC50 (3h) was determined to be > 100 mg/L (Sandoz 1988). Therefore, the test substance is considered not to be harmful to microorganisms.
EC 432-690-8: In a respiration rate study (3 h) of the test substance, no toxic effects occurred at the test concentration of nominally 1000 mg/L (Clariant 1999). Therefore the test substance is considered not to be harmful to microorganisms.
EC 476-900-6: In a respiration rate study (3 h) of the test substance, no toxic effects occurred at the test concentration of nominally 1000 mg/L (Clariant 2005). Therefore the test substance is considered not to be harmful to microorganisms.
EC 416-640-2: In a respiration rate study (3 h) of the test substance, no toxic effects occurred at the test concentration of nominally 1000 mg/L (Sandoz 1995). Therefore the test substance is considered not to be harmful to microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
