Cobalt Lithium Manganese Nickel Oxide

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

long-term toxicity to aquatic invertebrates

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Automatic calculation with MeCLas tool

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other: software

Title:

Unnamed

Year:

2014

Materials and methods

Principles of method if other than guideline:

Aquatic toxicity of NMC with typical composition was determined by classifying based on Mixture rules from EU CLP (Tier 2 = additivity of soluble components (T/Dp data) to derive Hazard class) and back calculation to the corresponding EC10/NOEC range

Test material

Test material information

Constituent 1

Reference substance name:

Nickel

EC Number:

231-111-4

EC Name:

Nickel

Cas Number:

7440-02-0

Molecular formula:

Ni

IUPAC Name:

nickel

Constituent 2

Reference substance name:

Cobalt

EC Number:

231-158-0

EC Name:

Cobalt

Cas Number:

7440-48-4

Molecular formula:

Co

IUPAC Name:

cobalt(2+)

Constituent 3

Reference substance name:

Manganese

EC Number:

231-105-1

EC Name:

Manganese

Cas Number:

7439-96-5

Molecular formula:

Mn

IUPAC Name:

Manganese

Constituent 4

Reference substance name:

Lithium

EC Number:

231-102-5

EC Name:

Lithium

Cas Number:

7439-93-2

Molecular formula:

Li

IUPAC Name:

lithium

Test material form:

solid: particulate/powder

Details on test material:

Composition represents a typical concentration of each individual consituent in NMC; it should be noted that the composition of actual NMC always meets the following stoechiometric criteria: Ni+Co+Mn = 1, Li =1-1.1, and O=2

Results and discussion

Effect concentrations

Duration:

21 d

Dose descriptor:

NOEC

Effect conc.:

> 0.1 - <= 1 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

other: most sensitive species

Any other information on results incl. tables

According to MeClas, the substance is classified as Aq.Chronic Cat.3 to the environment.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

Good quality estimate of the EC10/NOEC of NMC with typical composition.
The substance is classified as Aq.Chronic Cat.3 to the environment resulting in a EC10/NOEC <= 1 mg/L.

Executive summary:

The study provided a conservative estimate of the effect concentration, derived on basis of the classification outcome (mixture toxicity rules) from a typical NMC sample, using dissolution data that were generated with an NMC-sample. 

 

Validity of the model used:

1. Defined endpoint: the endpoint is a REACH compliant defined endpoint

2. Unambiguous algorithm: EU CLP guidance based summation formula to determine classification, followed by back-calculation to related hazard criteria

3. Applicability domain: applicable to classify complex metal containing materials. 

4. Mechanistic interpretation - metal species: the tool translates the elemental composition into a mineralogical composition relevant for classification.