Registration Dossier
Registration Dossier
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EC number: 251-529-0 | CAS number: 33456-68-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide
- EC Number:
- 251-529-0
- EC Name:
- p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide
- Cas Number:
- 33456-68-7
- Molecular formula:
- C20H22N2O5S
- IUPAC Name:
- 4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene-1-sulfonamide
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): AR-FD 26 ( phase X )
- Physical state: powder
- Lot/batch No.: 01010
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Factor X (used in the DBO5) prepared in the laboratory
- Duration of test (contact time):
- 28 d
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Temperature: 20° - 25° C
It is carried out in the darkness or under diffuse light.
Aeration or shaking, in order to ensure that the concentration of dissolved Oxygen is not less than 1 mg/L
Regulated pH of 6.5- 8.0 with NaOH (40 g/l) or H2S04 (50 g/l) if necessary
Carry out measurements of DQO (1, 7, 14, 21 and 28 day)
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 74
Any other information on results incl. tables
| Days of measurement of DQO | |||||
| Initial | 7 days | 14 days | 21 days | 28 days | |
| White | 5.0 | 7.0 | 13 | 6.0 | 4.0 |
| Standard | 693 | 640 | 458 | 448 | 399 |
| DQO(mg/l O2) | 134 | 54 | 67 | 32 | 37 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- other: Biodegradable Product
- Conclusions:
- AR-DF 26 Phase X is biodegradable (74%)
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