Registration Dossier
Registration Dossier
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EC number: 211-128-3 | CAS number: 630-08-0
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2012
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- As the substance is a gas, measured data for the toxicity to aquatic invertebrates are not available. In the place of measured data, predicted data using the QSAR model ECOSAR v.1.11. The substance is within the profile of the model and so the results are considered reliable
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR predicted data
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
- Principles of method if other than guideline:
- ECOSAR is a QSAR for organic substances which estimates the ecotoxicity based on structure-activity relationships.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Carbon monoxide
- EC Number:
- 211-128-3
- EC Name:
- Carbon monoxide
- Cas Number:
- 630-08-0
- Molecular formula:
- CO
- IUPAC Name:
- carbon monooxide
- Test material form:
- gas
Constituent 1
Test solutions
- Vehicle:
- not specified
Study design
- Test type:
- not specified
- Limit test:
- no
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 307.5 mg/L
- Remarks on result:
- other: QSAR predicted value
Applicant's summary and conclusion
- Conclusions:
- The 48 hr LC50 to daphnia was predicted to be 307.5 mg/L
- Executive summary:
No experimental data are available for the effect of the substance on the short term toxicity of invertebrates.The QSAR, ECOSAR Program v1.11 was used to predict the toxicity. The QSAR is acceptable with restrictions. The LC50 (48 hours) for daphnia is estimated to be 307.5 mg/L in fresh water
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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